I've a T2 diabetic friend. He's not allowed to eat grapefruit or pineapple. I'm wondering if this is because they do the same job as his pharma meds, and if he ate them he'd overdose his meds? Docs just told him to avoid them as they prevent meds working.
I read somewhere that grapefruit increases the potency of drugs. One specific example is statins that are supposed to become 10 times more powerful. Grapefruit is included in the artemisinin treatment in order to do just that - to increase the power of artemisinin by some orders of magnitude. As I do not take any prescription drugs, I do not have to worry about overdosing on them. Its not that they stop the meds from working, its that they make them work too well.
I was wondering if by taking the fruits, peels, if that would prevent the disease but it's probably more complicated with the reaction of the chemical compounds.
IF you use the peels you are getting quercetin as well as naringenin - there's a lot of powerful stuff going on with it. I'm gambling on it treating metabolic syndrome, but for now it seem to be making my blood sugar worse, not better.
Citrus peel has loads of antiviral phytonutrients besides quercetin and naringenin and it helps with Metabolic Syndrome and blood sugar generally but it also can make histamine excess worse. If allergy mast cells are being triggered then overall there would be a health negative rather than a benefit.
I used citrus peel in March 2020 with early outbreak CoV but eventually learned it was adding to my histamine mood symptoms and had to stop. But then my mood problems got better so it was a net gain. I use pomegranate peel as an antiviral, anti-inflammatory and it prevents mast cell degranulation.
"Co-researchers to help me flesh this out would be most appreciated. Who else is looking in this direction?" I Tweeted daily for over a year about citrus peel for CoV.
So what do you know about particularly grapefruit being contra-indicated for hormonal cancers, and do you know if all breast cancers are hormonal cancers? (My local doctor was unable to interpret my biopsy result to tell me what kind of breast cancer I apparently have.)
Remember that having to deal with cancers, plural, tends to take the principal focus away for CoV.
I am not having histamine reactions to the current set of neutraceuticals I am taking, even the grapefruit, and including the naringenin and the modified citrus pectin (my latest experiment as it is also a powerful detox agent). In fact my body seems to be loving all this grapefruit - perhaps even itching less - although it has pushed my blood sugar up, hopefully just temporarily.
I am working on the theory that the components of metabolic syndrome, when newly diagnosed after covid, have been caused by covid. Undoing the damage done by covid should allow them to return to "normal".
Metabolic syndrome is helped by bitter phytonutrients which includes naringenin and other citrus peel phytonutrients.
Extra magnesium is likely needed too for Metabolic Syndrome type symptoms, but rarely is mentioned. It is protective against cancer too. Methylation cycle function needs to be restored and that requires magnesium, B vitamins, CoQ10, glycine, methionine, and iodine is also not discussed as a needed nutrient for cancer or other conditions. Pomegranate peel inner pith is also a pectin source and pectin is directly protective against a spike created increase in galectin-3.
Are all breast cancers hormonal? I am not sure but I think they all likely involve low iodine and excess fluoride and bromide which is cancer promoting while iodine is protective.
Avoiding chicken broth and chicken products may help reduce food supply for breast cancer cells as they like arachidonic acid. Reducing inflammation in general would help because that causes more endocannabinoid release from membranes which then makes arachidonic acid as a breakdown product. Chicken cooked in a moist way is going to have more arachidonic acid then some other protein choices.
An external source of cannabinoids tends to be protective against cancer and pomegranate peel is very effective, particularly against metastasis.
In my 1950's childhood, my mother (like her mother before her) made candied orange and grapefruit peel---part of the Christmas preparation, like the very rich and intricately shaped cookies. I treated myself to a dehydrator two summers ago, and now I dehydrate, then powder, orange peel--and add it here and there to cooking. Same stuff, without all the sugar, and no cooking. Of course, maybe we will discover that heat is required to bring out the nutritive potential.
I think your dehydrated and powdered peel is a great idea. But as far as heat is concerned, I have been more concerned that the heat might damage the nutrients. But as naringenin is not very bio-available and our bodies struggle to extract and use it, perhaps it is more bio-available when extracted into water using heat. The research papers are not very forthcoming with "normal speak" so that we can interpret them for ourselves. (If I have understood the medical papers, it passes too fast through the digestion and from there into the blood or urine.)
The bio-availability seems to be the main limitation of using it commercially. I don't understand a word of the medical papers where they are discussing high tech techniques to render it more bio-available but it does not seem to be easy.
Thanks for your thoughtful response. One (of very many--and why on earth did I wait so long to get one?) of the things I like about the dehydrator, is being able to set the temp as low as 95 F all the way up to 145F. Certainly the candying of peel had it exposed to jellying temp of 230F.
Your article about a citrus fruit put me in mind of bergamot, a supplement we take. Interesting how many bioactive substances there are in citrus fruits.
My wife just warned me that grapefruit can aggravate arthritis.
...and for those who don't know, bergamot is high in naringenin. I have always been wary of bergamot because it can make the skin ultra sensitive to sunlight, which my very pale skin is, already. I am concerned with the long terms effects of taking something that is essentially corrosive, so I think it is something to use in support of other therapies and "pulsed" on and off, so the body has time to recover.
"Naringenin “(5,7-dihydroxy-2- (4-hydroxyphenyl) chroman-4-one)” is a flavanone that may be detected in grapefruit, oranges, and bergamot. Numerous therapeutic potentials of naringenin have already been described in a different study."
I've a T2 diabetic friend. He's not allowed to eat grapefruit or pineapple. I'm wondering if this is because they do the same job as his pharma meds, and if he ate them he'd overdose his meds? Docs just told him to avoid them as they prevent meds working.
I read somewhere that grapefruit increases the potency of drugs. One specific example is statins that are supposed to become 10 times more powerful. Grapefruit is included in the artemisinin treatment in order to do just that - to increase the power of artemisinin by some orders of magnitude. As I do not take any prescription drugs, I do not have to worry about overdosing on them. Its not that they stop the meds from working, its that they make them work too well.
I was wondering if by taking the fruits, peels, if that would prevent the disease but it's probably more complicated with the reaction of the chemical compounds.
IF you use the peels you are getting quercetin as well as naringenin - there's a lot of powerful stuff going on with it. I'm gambling on it treating metabolic syndrome, but for now it seem to be making my blood sugar worse, not better.
Citrus peel has loads of antiviral phytonutrients besides quercetin and naringenin and it helps with Metabolic Syndrome and blood sugar generally but it also can make histamine excess worse. If allergy mast cells are being triggered then overall there would be a health negative rather than a benefit.
I used citrus peel in March 2020 with early outbreak CoV but eventually learned it was adding to my histamine mood symptoms and had to stop. But then my mood problems got better so it was a net gain. I use pomegranate peel as an antiviral, anti-inflammatory and it prevents mast cell degranulation.
"Co-researchers to help me flesh this out would be most appreciated. Who else is looking in this direction?" I Tweeted daily for over a year about citrus peel for CoV.
I did some math on quercetin and hesperidin content in citrus peel. I just ate the fresh inner peel with the orange slices. The pectin is also anti CoV so making it into a boiled extract is unnecessary and losing some benefits of the whole peel. https://transcendingsquare.com/2020/04/14/hesperidin-and-quercetin-content-in-citrus-peel/
So what do you know about particularly grapefruit being contra-indicated for hormonal cancers, and do you know if all breast cancers are hormonal cancers? (My local doctor was unable to interpret my biopsy result to tell me what kind of breast cancer I apparently have.)
Remember that having to deal with cancers, plural, tends to take the principal focus away for CoV.
I am not having histamine reactions to the current set of neutraceuticals I am taking, even the grapefruit, and including the naringenin and the modified citrus pectin (my latest experiment as it is also a powerful detox agent). In fact my body seems to be loving all this grapefruit - perhaps even itching less - although it has pushed my blood sugar up, hopefully just temporarily.
I am working on the theory that the components of metabolic syndrome, when newly diagnosed after covid, have been caused by covid. Undoing the damage done by covid should allow them to return to "normal".
Metabolic syndrome is helped by bitter phytonutrients which includes naringenin and other citrus peel phytonutrients.
Extra magnesium is likely needed too for Metabolic Syndrome type symptoms, but rarely is mentioned. It is protective against cancer too. Methylation cycle function needs to be restored and that requires magnesium, B vitamins, CoQ10, glycine, methionine, and iodine is also not discussed as a needed nutrient for cancer or other conditions. Pomegranate peel inner pith is also a pectin source and pectin is directly protective against a spike created increase in galectin-3.
Are all breast cancers hormonal? I am not sure but I think they all likely involve low iodine and excess fluoride and bromide which is cancer promoting while iodine is protective.
Avoiding chicken broth and chicken products may help reduce food supply for breast cancer cells as they like arachidonic acid. Reducing inflammation in general would help because that causes more endocannabinoid release from membranes which then makes arachidonic acid as a breakdown product. Chicken cooked in a moist way is going to have more arachidonic acid then some other protein choices.
An external source of cannabinoids tends to be protective against cancer and pomegranate peel is very effective, particularly against metastasis.
In my 1950's childhood, my mother (like her mother before her) made candied orange and grapefruit peel---part of the Christmas preparation, like the very rich and intricately shaped cookies. I treated myself to a dehydrator two summers ago, and now I dehydrate, then powder, orange peel--and add it here and there to cooking. Same stuff, without all the sugar, and no cooking. Of course, maybe we will discover that heat is required to bring out the nutritive potential.
I think your dehydrated and powdered peel is a great idea. But as far as heat is concerned, I have been more concerned that the heat might damage the nutrients. But as naringenin is not very bio-available and our bodies struggle to extract and use it, perhaps it is more bio-available when extracted into water using heat. The research papers are not very forthcoming with "normal speak" so that we can interpret them for ourselves. (If I have understood the medical papers, it passes too fast through the digestion and from there into the blood or urine.)
The bio-availability seems to be the main limitation of using it commercially. I don't understand a word of the medical papers where they are discussing high tech techniques to render it more bio-available but it does not seem to be easy.
Thanks for your thoughtful response. One (of very many--and why on earth did I wait so long to get one?) of the things I like about the dehydrator, is being able to set the temp as low as 95 F all the way up to 145F. Certainly the candying of peel had it exposed to jellying temp of 230F.
Love the idea of the dehydrator. I had forgotten about that device. Hope to get one in the coming year. Would love to dry some citrus peel!
I put the dried peels through the coffee bean grinder (which only gets used for spices)
Very informative and detailed as always.
Your article about a citrus fruit put me in mind of bergamot, a supplement we take. Interesting how many bioactive substances there are in citrus fruits.
My wife just warned me that grapefruit can aggravate arthritis.
All the best.
...and for those who don't know, bergamot is high in naringenin. I have always been wary of bergamot because it can make the skin ultra sensitive to sunlight, which my very pale skin is, already. I am concerned with the long terms effects of taking something that is essentially corrosive, so I think it is something to use in support of other therapies and "pulsed" on and off, so the body has time to recover.
"Naringenin “(5,7-dihydroxy-2- (4-hydroxyphenyl) chroman-4-one)” is a flavanone that may be detected in grapefruit, oranges, and bergamot. Numerous therapeutic potentials of naringenin have already been described in a different study."
Your article is equal parts fascinating and helpful. Thank you.