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How I wish I could sit down with you and chat. When you’re in a bad place all these acronyms (COMT, MTHFR) and big words like methylation, are beyond comprehension.I don’t need a doctor, they just don’t care, and those that do only care when you pass them £££, which I don’t have. I need to figure things out…where do I go and who do I see?

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There are a few links at the start of the article to previous articles that talk about the genes and methylation. I don’t think I can reasonably summarise it in this article - never sure how to handle series of articles that cover too much to put in one. But you’re right, you don’t need a normal doctor, but you do need a geneticist of some kind. All our ill health comes from our innate genetic makeup and some aspect of our lives that does not suit that makeup. So we have to start from the genes.

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Hi Christine, I found a list of companies doing DNA testing. This one looks great, but I’ll have to save for 3 months to afford it.

https://nebula.org/whole-genome-sequencing-dna-test/.

Thanks for replying. I’ll read your earlier work, and yes need to make an effort to subscribe.

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Oct 17·edited Oct 17Author

There's lots of them with lots of different pricing and we presume, different packages delivered. I have not got through them yet to work out what I want and how to pay for it. For now, I have my ancestry dot com data in a text file. I ask ChatGPT about a particular gene, and how to find it and interpret it in my Ancestry data. So for example, it gives me the ancestry ID for the MTHFR gene. I run a search on the data file to find the ID and find what my genetic status is for that gene. I then ask ChatGPT to tell me what having those genetic variants means for me. I started with the MTHFR gene, then added the COMT gene, then the PEMT gene, and now the BHMT gene, as all of these impact on methylation. Each time I give ChatGPT new genetic information I ask it to tell me how to manage my diet and supplementation in the light of that data. This stuff can all be computerised if you get your genetic data in the first place, and then use ChatGPT to help you interpret it. The only unavoidable costs are the initial genetic tests, and if required, the supplementation, but for anyone with the disposable income, I would recommend they find an expert - I just don't know who those are yet.

In addition to getting ChatGPT to build up a picture of my genetic status, I have found it also very useful to give it health clues. I will tell it what has worked in the past for whatever we are talking about, and what has made it worse. The AI is able to analyse these against my genes and tell me why (a) works and (b) makes me worse, and how to do that more efficiently. As long as you are able to ask intelligent questions, ChatGPT is going to be better than 99.9% of available doctors. I would still like the human help if I could afford it - but I am getting along without it.

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