Genetics and AI have given us an opportunity we have never had before...
...and maybe will not have for long and maybe will never have again.
I am unvaxxed
The information provided on this article does not, and is not intended to, constitute medical advice; instead, all information, content, and materials available on this site are for general informational purposes only.
We must ALL understand our genes
If we are to survive the assaults on our health via all kinds of biological and chemical challenges, we must understand how to support our genes to keep us in the best health possible. We cannot maintain our health in the current environmental conditions without understanding our genes.
Are you afraid of genetic testing?
When I rave to anyone who will listen about the importance of genetic testing - of understanding our own genes, I hit a roadblock, a very similar roadblock to when I rave to those same people about the importance of learning to use AI. People are afraid.
Being personally targeted
They are afraid of having genetic tests done because they are afraid of being targeted by some kind of advanced weaponry, that can make them ill and take them out. But seriously, you and I are just not that important. No-one is targeting my body or your body. I am not saying that they cannot target individuals personally, but that most of us don’t matter enough to be targeted personally. If they were going to target anyone personally, it would be people with huge followings who can do huge harm. It doesn’t matter how much most of us know or don’t know, we do not have the power to threaten them, so they will leave us alone - as individuals.
Being targeted as a group
But that does not mean they will leave us alone as a racial group or haplogroup. They don’t need to target us personally. They have mapped the entire human genome, meaning they know all the 20,000-25,000 genes that humans can have, even if they do not yet know what they all do. If they direct a bio-weapon or toxin at a single known gene out of the entire pool of genes, they can potentially damage millions of us who share that gene, in one hit - which may be exactly what they were trying to do with “covid”, or “5G”, four years ago and with the vaccine program before and since.
If we can’t stop them contaminating our world, we can at least enhance our ability to deal with that contamination, and that is what we get when we study our genes.
One gene that really matters is the MTHFR gene
One set of gene variants that is shared by 40-60% of the global population are the MTHFR gene variants. I am not going to explain here how this works - or rather doesn’t work - but somewhere between 40-60% of us have a genetic variant that messes up our ability to effectively process optimal amounts of vitamin B9, and this simple shortfall has massive downstream consequences. After we consume naturally occurring B9 in our kale and spinach smoothies, our body has to change the chemical form of that B9 so that it can be used for a variety of critical bodily functions. But if our bodies cannot change the chemical form of enough of the naturally occurring B9 (folate) that we consume - those of us with MTHFR variations can be from 20% compromised to 80% compromised - then some downstream functions are simply not going to work or work well enough and no amount of good diet is going to fix it!
A compromised MTHFR gene can lead to an impressive array of downstream health issues due to impaired methylation (you will need to learn about methylation, methyl groups, and methyl donors to get on top of any MTHFR issues). If you have a seriously compromised MTHFR gene you need to know! Here’s a bullet point summary of the downstream health issues:
Elevated homocysteine levels: Increases risk of cardiovascular diseases (e.g., heart disease, stroke, blood clots).
Folate deficiency: Can contribute to anemia, poor cellular repair, and neural tube defects in pregnancy.
Mental health disorders: Linked to depression, anxiety, bipolar disorder, and schizophrenia due to impaired neurotransmitter synthesis.
Chronic fatigue: Reduced energy production and mitochondrial function.
Inflammation and oxidative stress: Due to impaired detoxification pathways.
Inability to detox: Reduced capacity to eliminate toxins, heavy metals, and environmental pollutants, leading to toxin accumulation and increased risk for various health issues.
Hormonal imbalances: Affecting estrogen metabolism and adrenal function.
Recurrent miscarriage and fertility issues: Linked to methylation-related fertility problems.
Cognitive decline: Impacts on brain function, memory, and risk for Alzheimer’s disease.
Fibromyalgia and chronic pain syndromes: Possibly due to impaired neurotransmitter function and inflammation.
Increased cancer risk: Poor DNA repair and abnormal cell growth.
But its not all doom and gloom - we can stop the MTHFR gene from harming us
The MTHFR is possibly the most prevalent and secretive gene we are dealing with, and its consequences manifest as disease a long way from the source. I call it secretive because we can live our entire lives not knowing we carry this gene. We can spend our entire lives, as I have, never being 100% of the person we should be, and not knowing why. Doctors do not know what is wrong with us and all manner of alternative practitioners do not know what is wrong with us either. They all rob us blind, as they gaslight us with stories that, if we make their chosen package of lifestyle changes or take particular drugs, we WILL get better, but which, in our experience, ALWAYS makes us worse.
We cannot see that this gene is making us sick and we cannot identify that it is the source of many downstream illnesses, unless we know it is there and take steps to control the outcomes.
Let me stress again that somewhere between 40% and 60% of the human population has some degree of impairment of the MTHFR gene. That’s an awful lot of people who need to know they have this gene variant and how to manage it successfully.
Understanding B9
I alluded to the problem with B9 earlier in this article. There are a number of forms of B9 and we need to know how our body processes it to know how to take control of our health and initiate deep and fundamental healing.
Below is a list of the different chemical forms of B9 (folate) and how they differ. The key difference is how easily each form can be metabolized and used, especially for individuals with compromised MTHFR function.
Folate (natural): Found in foods like leafy greens; requires conversion to 5-MTHF for use in the body. With the MTHFR genetic variants, your body may have from a 20% to an 80% capacity to process enough of the folate into 5-MTHF.
Normal B complex vitamin supplements contain this form of B9 which is not particularly useful for those with MTHFR variants.
Folinic acid (5-formyl THF): Active, naturally occurring form; found in the same foods as folate, bypasses some conversion steps, easier for the body to use, but not found in sufficiently high levels to replace the need for folate.
Sometimes taken as a supplement.
5-MTHF (5-methyltetrahydrofolate): Fully active form, directly usable by the body, only found in tiny amounts in foods; preferred for those with MTHFR mutations.
Often supplemented by those with MTHFR variants
Folic acid: Synthetic form found in supplements and fortified foods; needs to be converted to its active form (5-MTHF) in the body. This is used by law in many Western countries to fortify 'white' wheat and rice products, baby products, etc. However, people with MTHFR gene variants—who already have reduced folate processing ability—do not efficiently convert folic acid, leading to unmetabolized folic acid in the bloodstream that may have as yet unknown long term damaging impacts.
Anecdotally known to be damaging for those with MTHFR variants and should be avoided by removing all fortified manufactured foods from the diet. Should not be taken as a supplement.
We must all learn to take control of our genetic variants
Understanding our genes
The first step to taking control of your health if you have the MTHFR variant is to get control of your B9, by avoiding foods you should avoid, adding foods with naturally occurring folate, and making sure your body can process what you are consuming by adding appropriate supplements.
It is, of course, not as simple as that. If you have this variant you need to research exactly what other genetic variants you have, that work together with the MTHFR gene. It is a massive and complex study and not for the faint-hearted, so this is where you might want to start.
Get onto some Facebook MTHFR support groups. At the very least you will stumble over questions you need to be asking.
Listen to, watch or read a few of the gurus. These are a few I have stumbled over, and they each have multiple forms of web presence. From them, you can learn all about B vitamins and methylation. It is critical you understand methylation. In no particular order these are the people I watch or listen to from time to time to make sure I am understanding the MTHFR issue:
Get a full genetic test done to provide the raw data. There are lots of services out there that will do genetic tests for you. If you already have an Ancestry or 23&ME genetic test, as I had, you can download and use that raw data.
Have the raw data run through a computer program to interpret your entire genetic makeup and tell you what genes are impacting on your health and suggest what remedial actions you can take. I have not fully investigated these companies, and what they offer, but there are many of them. Most are beyond my financial capacity to pay, but the following one is cheap by comparison and came recommended on a Facebook MTHFR support group. I will be recruiting at least this level of support, having realised I cannot wrap my brain around everything I need to wrap my brain around, in this lifetime.
Perhaps recruit ongoing personalised support to help you implement the results, or, if you cannot afford this, recruit ChatGPT or other AI to double check all your conclusions and potential actions. AI really can help where the budget cannot stretch to personalised support.
Understanding the ongoing need to supplement
Supplementing if you have some degree of MTHFR variant is often the best path to take, but depending upon which MTHFR variants and other genetic variants such as the COMT and PEMT genes - these genes can impact further for good or ill, on your ability to get the value you need out of B9. The story gets complex which is why you need a computer interpretation of all the genes that matter. There are too many genes with too many interrelationships for us to possibly get our human brains around all the variables - we must use computers to help us with this part of the process.
Understanding just how complex supplementing is
“One man’s meat is another man’s poison.” This is old English wisdom we have forgotten and must learn again once we understand the MTHFR gene. I might have variants that require different diet and different supplementation from your variants. What you must take might actually harm me. No decision on the best diet can possibly be made without knowing how your genes handle food.
Then add complexities of other closely related genes, and what it seems we must take for one genetic limitation is actually contra-indicated for another. This whole thing requires ongoing careful personal management, and the solution for one person cannot be applied to another. There is no “one size fits all” fix for this.
Understanding the ongoing need to detox
And no matter what MTHFR variants we have, we also have some level of detox compromise so we have to work out, as best we can, the safest and most sustainable ways to detox, for the rest of our lives! Our world is now far too toxic for us to expect MTHFR compromised bodies to be able to keep up with the rate of detox necessary to manage our toxic environment, even where we do everything possible to avoid toxins. We can NEVER make enough lifestyle changes to stop all toxic harms from entering our bodies. We have to support our detox process.
This is a fraught topic that I have been wanting to reach some resolution on myself, but I am still unsure of the right path to take. I personally avoid all chemical detox agents - just a cringe I have about taking them. I stick to plant based detox agents, which, even then, are fairly tampered with:
modified citrus pectin (for heavy metal detox and cancer management)
activated silica (for aluminium detox)
fulvic/humic acid (as a general mineral supplement and general detox aid)
We need AI as our ally to help us live in harmony with our genes
Getting over our fear of AI
Just as people are nervous about having genetic testing done, pretty much the same group of people are nervous about using AI. And my response is the same for both fears. There is nothing you or I can do, using the AI tools available to us, to change the future of the human relationship with AI by the tiniest degree.
Whether or not AI is planning to take over mankind, or whether or not malevolent human beings are planning to use AI to take us over, you and I can do nothing to change that.
Even if someone was watching Christine use her Ancestry genetic data, supported by a service that interprets that data using AI, and ChatGPT to double check everything, that information will change nothing. I don’t matter enough to warrant either the surveillance or the personal intervention.
I AM ALREADY DEAD.
They have already done their worst by unleashing a range of deadly bio-weapons and toxins, that 40% to 60% of the human population lack the genetic capacity to heal from. With my genetic variants, I am one of the worst affected of that 40 - 60%. I will not defeat them by hiding my genetic data, or refusing to use the best tools available to wrap my head around this stuff.
I will defeat them by learning how to manage my genetic limitations so they do NOT kill me, and sharing the results with anyone who will listen.
I can only do that by understanding my genetic data fully, and
I can only understand my genetic data fully, with the help of AI.
Understanding how to use AI
One way or another, once you are paying attention to genes, you are using AI. You are either outsourcing the job to companies whose business is to work with your genetic information, and provide you with a range of health related services, based on that information, or you are doing parts of it yourself.
Whether it is you or your provider analysing your data, you will need AI to help in the process.
I have been using ChatGPT to learn about how all this stuff works. I read stuff, I listen to stuff and I have outstanding questions with no way of finding the answers without paying experts. But I can ask ChatGPT. You have to be clever and vigilant with ChatGPT because it will omit information, and it does occasionally muddle information (like using the terms folate and folic acid interchangeably where they are vastly different and should never be confused). But it is much better than having no way of getting questions answered at all.
I have also used ChatGPT to come up with suggestions for what pathology tests I should ask my doctor to run, so that we can establish a base line, and then see, over a sustained period of time, how much supplementing at the genetic level, impacts upon downstream health markers.
I will get a report from Living with MTHFR to identify all my genetic risk factors and hopefully how they impact on one another. I can use ChatGPT to validate or dispute this information.
Once I get the pathology results, and the genetic report, I will settle on a supplementation plan, probably involving a mitochondrial support product like AgeMate, plus the correct form of B supplementation for my genetic type. We can give ChatGPT information on products and doses, and it will calculate to ensure we are not overdosing on a particular supplement, or missing critical supplements.
Then we wait
Human beings are impatient. We want to see a clear issue, visually, in some way, with our eyes, and then we want to see it go away, quickly. We have to see an illness directly through visible symptoms like a sore or a rash, or failing that, through test results from blood tests or X-rays etc. If we can’t see it, it’s not there, as everyone who has ever dealt with fibromyalgia or one of the pain syndromes knows. If you can’t see it, in some way, then it doesn’t exist, according to everyone but the person suffering it. Current diagnostics bring some of the invisible into the realm of the visible, but not ALL.
So what visible indicators can we devise to determine the effectiveness or otherwise of supplementing or making other lifestyle changes to circumvent genetic limitations? How do we make our healing visible when what we are treating is not visible?
I plan to do regular testing of agreed markers, potentially monthly, for a year, to assess just how much downstream impact there has been from intervening at the genetic level. When we work with the genes, we have no idea how our body has learned to work with the shortfalls we have, for our entire lives before this point, and we have no idea how it will adapt to having adequate and appropriate nutrients, for the first time in our lives.
My case study
Hopefully I will be able to document:
the range of significant genes for me and why they matter,
lifestyle changes to support management of those genes,
supplementation regimes to support management of those genes,
detox process and products that work,
agreed pathology testing and changes in significant indicators over time.
And I will also document what products have supported this process
the genetic testing companies I have dealt with and how well or badly they have supported this process
the supplements I have taken and how much they have needed adaptation
the lifestyle changes that have brought about most benefit, whether directly or indirectly.
That’s if some other crisis doesn’t intervene. Life happens.
Can you help?
I intend to keep writing of my journey through this rather strange time in my life, and for this planet. As soon as I know, I will share with you, what does and does not work to exorcise this bio-weapon from our bodies and take back some level of control of our lives.
If you think my writings are worthwhile, you can help me get more subscriptions and donations by sharing this article on other social media platforms, and by re-stacking this article in Substack Notes.
Or make a PayPal donation here to help with ongoing medical costs. Every little bit helps. The last donations, thank you, paid for a red light to help me find restful sleep, and experimental nitric oxide gummies to see if increasing nitric oxide levels improves my overall health (it does). I now have a non-intrusive blood glucose monitor. And soon it will pay for the proposed genetic testing and analysis. Thank you.
I agree with you about AI, and I agree with you about genetic testing with a caveat: it's probably patterns of groups of "bad" genetic factors working together to increase your risk of diseases rather than one single "bad" gene. Here's a good explanation (sorry you'll have to type it into search or cope and paste):
https://chriskresser.com/methylation-are-we-supplementing-too-much-with-dr-kara-fitzgerald/
And I 100% agree about detox!!!
Have you had a look at this company. Looks like they’ll do the heavy lifting for you, at a price of course.
https://www.lifecodegx.com/