2025: Genetics and AI, the future of 21st century healthcare

..perhaps now, those of us with underlying and unresolved health issues can at last find a pathway to the future, living the lives we want to live!

The information provided in this article does not, and is not intended to, constitute medical advice; instead, all information, content, and materials available on this site are for general informational purposes only.

Regular readers will have noted that I have not posted in a while. I was brought up with the mantra, “if you can’t say something good, then say nothing at all”, which, of course, I have not lived by. But it nags at me, and when everyone around me is putting on such a brave and smiley face, I find myself intimidated out of “telling it like it is” for me. Obviously, if I am the only person feeling a tiny bit challenged at the moment, it must be my fault. Hopefully I have moved through that, in the last month of re-evaluating my life, and I am ready to move on with some kind of optimism.

2024 was a shocking year for me

2024 was when I got two separate diagnoses of cancer, melanoma and breast cancer, the breast cancer identified while investigating for metastases from the melanoma. I was partly lucky - no metastases from either cancer, and partially unlucky in that both operations did not completely clear the tumours. So time will tell as to whether I get out of this alive.

My collapsing health started with hospitalisation in 2022, when I spent two weeks in solitary confinement in ICU, with what was called Covid. Once I returned home, my health did not recover. It was followed with what we are calling “Long Covid”, whatever that really is, with high blood pressure and high blood sugar both needing to be managed, a bout of shingles and then in 2024 with the two cancers. That’s a lot to contend with.

Currently, I have brought the high blood pressure and high blood sugar under control and, as far as I know, I am clear of both cancers. But once you have had cancer, if the cause has not been removed, you will get another cancer. I do not know that the cause has been removed, and if not, the cancer will recur – meaning I keep myself on maintenance doses of various alternative cancer treatment protocols, just in case – and will probably have to do so for whatever is left of my life.

Confronting my own mortality

One aspect of the shock of cancer diagnosis was to confront my own mortality, which I think I have done quite successfully. I may not live out this year 2025, and that is OK with me, or I may live to my 90s or 100s like most of my paternal female ancestors. Either way is fine. The big question is how to live out whatever remains of my life as well as possible, particularly when declining health is making it very difficult to do or achieve anything. So this is my plan.

Designing the next incarnation during this one

The Rosicrucians teach that we re-incarnate, and we should do what we can in this lifetime to create the life we want to experience next time around. So we cannot give up.

I never managed to create the life I wanted in this lifetime, so what on earth can I do to invest in the next one? I spent a lifetime trying to make this world a better place, and to find my place in that. I failed, but maybe that was the wrong thing to be doing all along. The only thing left to me now is to make myself a better person.

And at last I know what to do. If I have one year, or 20 years, left to live, how do I, from my current state of health and poverty, create a space that I would be happy to return to in a subsequent incarnation? As I can no longer do paid work, no longer earn decent money and no longer move around and travel, what can I do? What lifestyle can I craft to create a space for me to incarnate into next time? Well, I can still study, I can still research and I can still write, so that is what I will do.

My clash with “the world” this time round

In my late teens I realised that allopathic medicine was broken. I did not know how broken it was, but I knew it had no answers to what ailed me – Fibromyalgia since I was 14 – and that for most of the time doctors, and the world at large, blamed me for their inability to understand what I was experiencing. I got no help, either physically or emotionally, to deal with deep and unpredictable levels of pain. My pain forced me to detach from the world so that people could not harm me further, by demanding more of me than I was able to give.

I did not stop looking for a cure. I carted myself around every manifestation of our medical system, allopathic and alternative, and no-one had any answers that actually worked. In middle age I stumbled over a treatment that worked for me, but when I took that back to the medicos to ask for help refining it, I was simply told, by everyone I asked, that my treatment could not work. The pain of FMS along with its almost total denial by the rest of the world, set me up for isolation at best, and intellectual clash at its worst.

It has not been a smooth ride.

Then, Covid exposed to the whole world that allopathic medicine is broken, totally and hopelessly broken, and I was glad for that, but still no-one had any answers for me. Post my run-in with Covid in 2022, I lost control of the FMS and although my treatment of 30+ years was still helpful, it was no longer good enough to give me my life back.

And then the lights went on - 21st century medicine

At 72 my life had ground to a halt. I am now 74, and maybe I have found my new beginning, my reason for living, and my investment in my next incarnation.

Somehow, I landed on what I will call 21^st century medicine. 21^st century medicine focuses on the health of the whole being, not the diseases they manifest. It carries some hope that, even at my age, I can cure the FMS and reclaim my last one year, or twenty years of life, with healthy aging, able to do whatever I decide I want to do.

It’s all about genetics and food, with AI to help us put it all together

And the source of the light? Genetics, in league with AI. I can’t believe where I find myself today, advocating that everyone learn as much about their genetics as they can, and learn how to use AI to support that learning, because without AI, genetics is vastly too complex for we mere humans to wrap our heads around.

These two words, genetics and AI, separately and together, elicit huge levels of fear in people who have not yet discovered how empowering they are. We fear what laboratory monsters will do to us using genetics, and we fear what AI will do to us if used by some malevolent force against us, and those fears are legitimate.

But we will not escape either fate by running away from those fears. If genetics and if AI, are going to be used by the bad guys to harm us, then avoiding them is not going to stand in their way. They are coming for us anyway, and our best recourse is to understand them as best we can, and use them to enhance our own lives and strengthen us where possible.

Working with AI has been life-changing for me

What I have learned in just a few months of researching my own genetics and using AI to help me, has been utterly life-changing, which is no mean feat at 74. It is hard for me to believe that I only started writing about genetics and AI in September 2024 and what a journey it has been. My life is utterly changed, as I have worked to integrate the changed mindset we must all develop, to benefit from understanding our genetics.

I complain a lot about the mindsets of allopathic medicine and most of what masquerades as alternative medicine. They are fundamentally wrong in the way they approach health. They both start from a set of symptoms that is diagnosed as a disease, to which they then apply the prescribed treatment for that disease. Rarely does the person who went to the therapist for help get a look in. The therapist should, but rarely does, start from the person, and not just the person but their detailed genetics. Only once they understand the genetics can they know why the human being with their ailing body, has walked into their consulting room, and why they are seeking help. I will explain how this works in a moment.

Only once they understand the genetics can they know how to help that person.

In so little time, since September, I have been working on a whole host of genetic variants that define how I relate to the environment I am living in. It has become very clear to me that what is good for one person could be bad for me. Good is often bad, bad is often not so bad and maybe even good for someone else.

Nothing about health is as we have believed it to be! Nothing!

Let me tell you a short story about genetics to illustrate how important they are

MTHFR

Would you believe that the MTHFR variants mean that I must never ever again eat any food product that has been fortified with folic acid (all wheat flour products, by law), as my body cannot use it and it will gum up the folate receptors, meaning that they are no longer available for the essential naturally occurring folate. Bad stuff. Bad results.

COMT

And my COMT gene variants mean that even were I to get enough dietary folate converted to carry essential methyl groups to elsewhere in my body, those genes will not let it through. They will slow it down, leaving methyl groups hanging around with nothing much to do, and that means they cause trouble. Unused methyl groups - good stuff when used properly, are now causing massive levels of anxiety. The more good folate with good methyl groups left hanging around, the worse my anxiety state will be. So lessons learned, don’t EVER supplement with B vitamins that contain folic acid, and don’t ever supplement with methylated B vitamins if you already have enough or too much for your COMT speed. Good stuff. Bad results.

PEMT

But now let’s see. Choline can replace folate methyl groups to some extent, and so take some pressure off the MTHFR/COMT system. And there are lots of ways for the body to get choline. Just some bodies need vastly more of it than others, particularly those with MTHFR variants and slow COMT, like mine. The treatment I used successfully for 30+ years for my FMS was lecithin, which is very high in choline. Without knowing it, I was supplementing with choline. It worked, when every expert told me it couldn’t work. How much do they know? I was right all along. It does work, but according to Chris Masterjohn, I need about twice what I am getting, even with my lifelong high levels of supplementation. Good stuff. Good results but maybe need more.

CYP2R1, and VDR

And what doctor doesn’t nag us to get our vitamin D levels up, but the one they measure - the storage form, is always low in my case, because my genes process it into the active form immediately and rapidly. And doctors don’t measure the active form. Tricky stuff. Did you know every cell in your body can store Vitamin D, particularly fat? We simply don’t know enough about it to be mega-dosing with it. And if you take too much you will mess up your thyroid function. Dangerous stuff! Take care. This Facebook Group will give you some idea, but maybe leave you even more confused than ever.

LCT

But there is one bit of really really good news for me! My genes DO process milk. Go away you manufactured milk advocates, I have always eaten dairy, I can eat dairy and I will die eating dairy. I have always known that milk is medicine - for me!

Here is an article for milk lovers who have been intimidated out of consuming dairy. You might be one of the lucky ones too.

The above genes are the genes I am currently working to understand. There are lots of other genes that matter, but these are the starting point and are so complex, I can’t get on to others just yet.

COMT in pain disorders

Do you remember the protocol advocated for treatment of covid and recovery from long covid, that contained Quercetin as the key ingredient (for those who could not access recommended drugs)? The alternative covid protocols almost all contained Quercetin. Guess what?

Did you know, quercetin is bad for some of us?

I have been taking Quercetin since I was hospitalized in 2022! Quercetin might be why I have not recovered from my hospitalisation. Quercetin may have kept me sick for 2 1/2 years and counting. Why? Because it slows COMT even further, which slows methylation, which keeps every cell and every process in my body starving for methyl groups to do what they have to do. Even slower COMT means even slower healing and recovery!

Quercetin bad (for me). Resveratrol good (for me). Little did I know. I have stopped taking Quercetin now, and time will tell. Will my FMS symptoms improve? Green tea and elderberry are also bad. Gosh, I make my own elderberry tincture - that has to go! Drat.

If methylation is a mystery to you, you might want to learn about it here.

It's all about methylation: everything you didn't know, you need to know, about methylation

Living the life your genes want you to live

The details of my journey mean nothing to you because your combination of genes and genetic variants is utterly different from mine, and what is good or bad for me, will not necessarily be good or bad for you. The only genetic variants that matter to you are your own genetic variants.

I just tell you my story so you can see why no doctor and no naturopath in my entire life has ever been able to help me. Nor could they. Nor will they until they learn about genetics.

If you have had something elusive wrong with you that nothing has fixed, then take a good long look at your genes. You are very likely to find the answer there. Genes define your relationship with your environment, and understanding what your particular set of genes is demanding of you, will give you the key to a long and healthy life.

Sources of support

There are lots of sources of support on-line, Facebook groups, “expert” individuals and resource websites.

1. To get started on your journey you will need a comprehensive genetic test. Most seem to use 23andMe or Ancestry genetic tests. I have an old Ancestry test. They come on special regularly.

2. Then you can run those tests through on-line utilities.

• Some are entirely free like Genetic Genie and they are a good place to start while you learn how valuable this knowledge is.

• I have moved onto Genetic Lifehacks which has a minimal monthly fee but has so much valuable information, I am letting my monthly subscription run and paying up. The screen dumps above are from documents generated by Genetic Lifehacks from my Ancestry data and the COMT image is from one of their articles. If you are really broke you could take out a 1 month subscription and download all the reports you think you need. That’s what I intended to do until I realised how valuable this site is. If you sign up with their website and go through this link, I will receive a small affiliate payment which will help me pay their subscription. [Note: I cannot get the affiliate link working properly on each type of Substack interface - I will keep coming back to it until I do. Until this time, you may need to cut and paste the address if you want to sign up via my link.]

https://www.geneticlifehacks.com?aff=ChristineMargaret

https://www.geneticlifehacks.com?aff=ChristineMargaret

Genetic Lifehacks also have a Substack Account with a longevity focus.

You can also run a search to find Facebook support groups for specific gene variants - there are lots around. Some are more useful than others, but I will leave you to work out which are valuable for you. This is a huge field and I suspect we are all stumbling around in it blindfolded. But what we trip over can be invaluable.

Can you help?

I intend to keep writing of my journey through this rather strange time in my life, and strange time for this planet. As soon as I know what does and does not work to recover from this bio-weapon assailing our bodies, and what helps us take back some level of control of our lives, I will share that with you.

If you think my writings are worthwhile, you can help me get more subscriptions and donations by sharing this article on other social media platforms, and by re-stacking this article in Substack Notes.

Or you can make a PayPal donation here to help me with ongoing medical costs, as I confront recovery from the bio-weapon. Every little bit helps. Donations have helped me pay for health support that I could not otherwise have afforded, and that may help me see out my allotted days in the best health possible. I won’t be wasting any more money on Quercetin, that is for sure!